Research and Studies 2016-11-21T22:32:59+00:00
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Research and Studies

Concern about the dangerous impact of the chemicals found in our water, our air, and the personal products we use every day is no longer viewed with skepticism, or considered “science fiction”. Mainstream medical organizations are now banding together to spread the word about the numerous health impacts of these chemicals. Most recently, the International Federation of Gynecology and Obstetrics (FIGO) issued a statement in October 2015 warning that, “widespread exposure to toxic environmental chemicals threatens healthy human reproduction.”

This statement echoes the sentiments of other researchers and doctors, across many medical specialties. In a press release issued by the Endocrine Society, Andrea C. Gore, Professor at the University of Texas at Austin stated, “The evidence is more definite than ever before – EDCs (endocrine-disrupting chemicals) disrupt hormones in a manner that harms human health. Hundreds of studies are pointing to the same conclusion, whether they are long-term epidemiological studies in humans, basic research in animals and cells, or research into groups of people with known occupational exposure to specific chemicals.”

A study just completed found that pregnant women with higher levels of BPA in their blood were more likely to deliver their babies early compared with women with lower levels of BPA. Other research has shown a link between BPA levels and polycystic ovary syndrome (PCOS). Studies involving male fertility have found that high levels of BPA in men’s urine correlates directly to lower sperm count. While BPA is one of the more researched EDCs, data exposing the harmful effects of other EDCs is rapidly building. A New York Times article warns that “the chemical industry has inherited the mantle of Big Tobacco, minimizing science and resisting regulation in ways that cause devastating harm to unsuspecting citizens.

Studies/References

The following references represent a very small sample of the total amount of scientific and medical literature that has been published in the area of reproductive toxicology and nutritional/dietary detoxification support.

Colbern T, Dumanoski D, Peterson Myers J. Our Stolen Future. Plume/Penguin Books, 1997.

Hollander D. Environmental effects on reproductive health: The endocrine disruption hypothesis. Family Planning Perspectives 1997 Mar/April; 29(2): 83-89.

Barrett JR. Fertile grounds for inquiry: Environmental effects on human reproduction. Environmental Health Perspectives 2006 November; 114(11): A644-A649.

Cohen M. ‘Detox’: science or sales pitch? Australian Family Physician 2007 December; 36(12): 1009-1010.

Zama AM and Uzumcu M. Epigenetic effects of endocrine-disrupting chemicals on female reproduction: An ovarian perspective. Neuroendocrinol 2010 October; 31(4): 420-439. (Note: this paper is a comprehensive review and includes 357 references)

Clinical Proceedings: Environmental impacts on reproductive health. Association of Reproductive Health Professionals, January 2010.

Barot S. BPA-free and beyond: Protecting reproductive health from environmental toxins. Guttmacher Policy Review 2010 Winter; 13(1): 18-22.

Richardson CT. Environmental justice campaigns provide fertile ground for joint efforts with reproductive rights advocates. Guttmacher Policy Review 2006 Winter; 9(1): 14-17.

Wong EW and Cheng CY. Impacts of environmental toxicants on male reproductive dysfunction. Trends Pharmacol Sci 2011 May; 32(5): 290-9.

Cheng CY, Wong EW, Lie PP, Li MW, Su L, Siu ER, Yan HH, Mannu J, Mathur PP, Bonanomi M, Silvestrine B, Mruk DD. Environmental toxicants and male reproductive function. Spermatogenesis 2011 Jan; 1(1); 2-13.

Phillips KP and Tanphaichitr N. Human exposure to endocrine disrupters and semen quality. J Toxicol Environ Health B Crit Rev 2008 Mar; 11(3-4):188-220.

Kumar S. Occupational, environmental and lifestyle factors associated with spontaneous abortion. Reprod Sci 2011 Oct; 18(10): 915-30.

Red RT, Richards SM, Torres C, Adair CD. Environmental toxicant exposure during pregnancy. Obstet Gynecol Surv 2011 Mar; 66(3):159-69.

Calcium D-Glucarate. Alternative Medicine Review 2002; 7(4): 336-339. (Note: this monograph reviews all of the scientific literature on d-glucaric acid through 2001)

Hanausek M, Walaszek Z, Slaga TJ. Detoxifying cancer causing agents to prevent cancer. Integr Cancer Ther 2003 Jun; 2(2): 139-44.

Zhao ZY. Liang L. Fan X. Yu Z. Hotchkiss AT. Wilk BJ. Eliaz I. The role of modified citrus pectin as an effective chelator of lead in children hospitalized with toxic lead levels. Altern Ther Health Med 2008 Jul-Aug; 14(4): 34-8.

Eliaz I, Weil E, Wilk B. Integrative medicine and the role of modified citrus pectin/aglinates in heavy metal chelation and detoxification – five case reports. Forsh Komplementmed 2007 Dec; 14(6):358-364.

Eliaz I, Hotchkiss AT, Fishman ML, Rode D. The effect of modified citrus pectin on urinary excretion of toxic elements. Phytother Res. 2006 Oct; 20(1):859-864.

Loguercia C and Festi D. Silybin and the liver: From basic research to clinical practice. World Journal of Gastroenterology 2011 May; 17(18): 2288-2301. (Note: this paper is a comprehensive review of all of the scientific literature available on Milk Thistle)

Yan F, Polk DB. Probiotics and immune health. Curr Opin Gastroenterol 2011 Oct; 27(6): 496-501.

Kopp-Hoolihan L. Prophylactic and therapeutic uses of probiotics: A review. J Am Diet Assoc 2001 Feb; 101(2): 229-38.

Konturek PC, Brzozowski T, Konturek SJ. Stress and the gut: pathophysiology, clinical consequences, diagnostic approach and treatment options. J Physiol Pharmacol 2011 Dec; 62(6):591-9.

Khani s, Hosseini HM, Taheri M, Nourani MR, Imani Fooladi AA. Probiotics as an Alternate Strategy for Prevention and Treatmnet of Human Diseases: A review. Inflamm Allergy Drug Targets 2012 Jan 20 [Epub ahead of print]

Kaur IP, Chopra K, Saini A. Probiotics: potential pharmaceutical applications. Eur J Pharm Sc 2002 Feb; 15(1): 1-9.

Schutz K, Carle R, Schieber A. Taraxacum -a review on its phytochemical and pharmacological profile. J Ethnopharmacol 2006 October 11; 107(3): 313-23.

Murray, Michael and Pizzorno, Joseph. Encyclopedia of Natural Medicine (revised 2nd edition). Prima Health, 1998.

Brown, Donald J. Herbal Prescriptions for Health and Healing. Prima Health, 2000.

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